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PXD011381-1

PXD011381 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleThe role of ptpn21 in hematopoietic stem cells
DescriptionTo identify the downstream substrate/effector that mediates Ptpn21 function. We applied comprehensive phosphoproteomics analysis with Lin- cells isolated from Ptpn21-/- and Ptpn21+/+ mice. The analysis revealed many pTyr sites on molecules associated with cytoskeleton. Additionally, we present a list of Ptpn21-dependent targets and putative substrates including Septin1 with increased tyrosine phosphorylation.
HostingRepositoryiProX
AnnounceDate2018-10-17
AnnouncementXMLSubmission_2018-10-16_22:08:40.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterFang Ni
SpeciesList scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Fusion
Dataset History
RevisionDatetimeStatusChangeLog Entry
02018-10-16 20:26:26ID requested
12018-10-16 22:08:41announced
22023-03-01 20:50:14announced2023-03-02: Update publication information.
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: ptpn21,biomechanics, septin1
Contact List
Cheng-Kui Qu
contact affiliationEmory University
contact emailchengkui.qu@emory.edu
lab head
Fang Ni
contact affiliationEmory University
contact emailfang.ni@emory.edu
dataset submitter
Full Dataset Link List
iProX dataset URI