PXD009338-1
PXD009338 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Protein Interactions of 7 MLL-fusion Proteins |
Description | MLL-fusions represent a large group of leukemia drivers, whose diversity originates from the vast molecular heterogeneity of C-terminal fusion partners of MLL protein. While studies of selected MLL-fusions have revealed critical molecular pathways, unifying mechanisms across all MLL-fusions remain poorly understood. We present the first comprehensive survey of protein-protein interactions of seven distantly related MLL-fusion proteins: MLL-AF1p, MLL-AF4, MLL-AF9, MLL-CBP, MLL-EEN, MLL-ENL and MLL-GAS7. |
HostingRepository | PRIDE |
AnnounceDate | 2018-05-25 |
AnnouncementXML | Submission_2018-05-25_00:57:10.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Alexey Stukalov |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | LTQ Orbitrap Velos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2018-03-27 00:04:24 | ID requested | |
⏵ 1 | 2018-05-25 00:57:12 | announced |
Publication List
Skucha A, Ebner J, Schm, ö, llerl J, Roth M, Eder T, C, é, sar-Razquin A, Stukalov A, Vittori S, Muhar M, Lu B, Aichinger M, Jude J, M, ü, ller AC, Gy, ő, rffy B, Vakoc CR, Valent P, Bennett KL, Zuber J, Superti-Furga G, Grebien F, MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity. Nat Commun, 9(1):1983(2018) [pubmed] |
Keyword List
curator keyword: Biomedical |
submitter keyword: human, MLL-fusion, leukemia |
Contact List
Florian Grebien | |
---|---|
contact affiliation | Ludwig Boltzmann Institute Cancer Research, Vienna, Austria |
contact email | florian.grebien@lbicr.lbg.ac.at |
lab head | |
Alexey Stukalov | |
contact affiliation | Technical University of Munich |
contact email | alexey.stukalov@tum.de |
dataset submitter |
Full Dataset Link List
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/05/PXD009338 |
PRIDE project URI |
Repository Record List
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