PXD008588-1

PXD008588 is an original dataset announced via ProteomeXchange.

Title	Genomic and Proteomic characterization of Aspergillus niger isolated from the International Space Station
Description	Genomic and proteomic characterization of the Aspergillus niger isolate, JSC-093350089, collected from U.S. segment surfaces of the International Space Station (ISS) is reported, along with a comparison to the experimentally established strain ATCC 1015. Whole-genome sequencing of JSC-093350089 revealed enhanced genetic variance when compared to publicly available sequences of A. niger strains. Analysis of the isolate’s proteome revealed significant differences in the molecular phenotype of JSC-093350089, including increased abundance of proteins involved in the A. niger starvation response, oxidative stress resistance, cell wall integrity and modulation, and nutrient acquisition. Together, these data reveal the existence of a distinct strain of A. niger onboard the ISS and provide insight into the molecular phenotype that is selected for by melanized fungal species inhabiting spacecraft environments.
HostingRepository	PRIDE
AnnounceDate	2018-08-21
AnnouncementXML	Submission_2018-08-21_11:35:09.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Abby Chiang
SpeciesList	scientific name: Aspergillus niger; NCBI TaxID: 5061;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2018-01-03 01:36:37	ID requested
⏵ 1	2018-08-21 11:35:10	announced
2	2019-02-26 07:59:24	announced	Updated publication reference for PubMed record(s): 30246146.

Dataset with its publication pending

curator keyword: Biological

submitter keyword: Proteomic, Aspergillus niger, International Space Station

Markus Kalkum
contact affiliation	Beckman Research Institute of City of Hope
contact email	mkalkum@coh.org
lab head
Abby Chiang
contact affiliation	City of Hope
contact email	jchiang@coh.org
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/08/PXD008588

PRIDE project URI

• PRIDE
  1. PXD008588
     1. Label: PRIDE project
     2. Name: Genomic and Proteomic characterization of Aspergillus niger isolated from the International Space Station