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PXD008588 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleGenomic and Proteomic characterization of Aspergillus niger isolated from the International Space Station
DescriptionGenomic and proteomic characterization of the Aspergillus niger isolate, JSC-093350089, collected from U.S. segment surfaces of the International Space Station (ISS) is reported, along with a comparison to the experimentally established strain ATCC 1015. Whole-genome sequencing of JSC-093350089 revealed enhanced genetic variance when compared to publicly available sequences of A. niger strains. Analysis of the isolate’s proteome revealed significant differences in the molecular phenotype of JSC-093350089, including increased abundance of proteins involved in the A. niger starvation response, oxidative stress resistance, cell wall integrity and modulation, and nutrient acquisition. Together, these data reveal the existence of a distinct strain of A. niger onboard the ISS and provide insight into the molecular phenotype that is selected for by melanized fungal species inhabiting spacecraft environments.
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAbby Chiang
SpeciesList scientific name: Aspergillus niger; NCBI TaxID: 5061;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Fusion
Dataset History
RevisionDatetimeStatusChangeLog Entry
02018-01-03 01:36:37ID requested
12018-08-21 11:35:10announced
22019-02-26 07:59:24announcedUpdated publication reference for PubMed record(s): 30246146.
Publication List
Romsdahl J, Blachowicz A, Chiang AJ, Singh N, Stajich JE, Kalkum M, Venkateswaran K, Wang CCC, Characterization of Aspergillus niger Isolated from the International Space Station. mSystems, 3(5):(2018) [pubmed]
Keyword List
curator keyword: Biological
submitter keyword: Proteomic, Aspergillus niger, International Space Station
Contact List
Markus Kalkum
contact affiliationBeckman Research Institute of City of Hope
contact emailmkalkum@coh.org
lab head
Abby Chiang
contact affiliationCity of Hope
contact emailjchiang@coh.org
dataset submitter
Full Dataset Link List
Dataset FTP location
PRIDE project URI
Repository Record List
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