PXD008237-1
PXD008237 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Mouse liver and kidney proteome with antibiotics treatment |
Description | Dysbiosis (alteration of intestinal flora) is associated with various host physiologies, including diseases. The purpose of this study was to clarify the effect of dysbiosis on protein expression levels in mouse liver and kidney by quantitative proteomic analysis, focusing in particular on drug-metabolizing enzymes and transporters in order to investigate the potential impact of dysbiosis on drug pharmacokinetics. |
HostingRepository | jPOST |
AnnounceDate | 2018-01-01 |
AnnouncementXML | Submission_2017-12-31_07:00:14.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Sumio Ohtsuki |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | iodoacetamide derivatized residue; (2S,3R)-3-hydroxyaspartic acid; L-aspartic 4-phosphoric anhydride |
Instrument | TripleTOF 5600 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2017-11-19 02:01:43 | ID requested | |
⏵ 1 | 2017-12-31 07:00:15 | announced | |
2 | 2018-09-19 00:40:52 | announced | Updated CV, FTP location and Modification list. |
3 | 2021-02-04 17:31:56 | announced | 2021-02-04: Updated FTP location. |
4 | 2022-09-18 03:00:58 | announced | 2022-09-18: Updated FTP location. |
Publication List
Kuno T, Hirayama-Kurogi M, Ito S, Ohtsuki S, Effect of Intestinal Flora on Protein Expression of Drug-Metabolizing Enzymes and Transporters in the Liver and Kidney of Germ-Free and Antibiotics-Treated Mice. Mol Pharm, 13(8):2691-701(2016) [pubmed] |
Keyword List
submitter keyword: mouse, liver, kidney, antibiotics, microbiome |
Contact List
Sumio Ohtsuki | |
---|---|
lab head | |
Sumio Ohtsuki | |
contact affiliation | Kumamoto University |
dataset submitter |
Full Dataset Link List
jPOST dataset URI |