PXD008237

PXD008237 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Mouse liver and kidney proteome with antibiotics treatment
Description	Dysbiosis (alteration of intestinal flora) is associated with various host physiologies, including diseases. The purpose of this study was to clarify the effect of dysbiosis on protein expression levels in mouse liver and kidney by quantitative proteomic analysis, focusing in particular on drug-metabolizing enzymes and transporters in order to investigate the potential impact of dysbiosis on drug pharmacokinetics.
HostingRepository	jPOST
AnnounceDate	2018-01-01
AnnouncementXML	Submission_2022-09-18_03:00:57.558.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sumio Ohtsuki
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	S-carboxamidomethyl-L-cysteine; L-methionine sulfoxide; O-phospho-L-serine; O-phospho-L-threonine
Instrument	TripleTOF 5600

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2017-11-19 02:01:43	ID requested
1	2017-12-31 07:00:15	announced
2	2018-09-19 00:40:52	announced	Updated CV, FTP location and Modification list.
3	2021-02-04 17:31:56	announced	2021-02-04: Updated FTP location.
⏵ 4	2022-09-18 03:00:58	announced	2022-09-18: Updated FTP location.

Publication List

Kuno T, Hirayama-Kurogi M, Ito S, Ohtsuki S, Effect of Intestinal Flora on Protein Expression of Drug-Metabolizing Enzymes and Transporters in the Liver and Kidney of Germ-Free and Antibiotics-Treated Mice. Mol Pharm, 13(8):2691-701(2016) [pubmed]

Kuno T, Hirayama-Kurogi M, Ito S, Ohtsuki S, Effect of Intestinal Flora on Protein Expression of Drug-Metabolizing Enzymes and Transporters in the Liver and Kidney of Germ-Free and Antibiotics-Treated Mice. Mol Pharm, 13(8):2691-701(2016) [pubmed]

Keyword List

submitter keyword: mouse, liver, kidney, antibiotics, microbiome

submitter keyword: mouse, liver, kidney, antibiotics, microbiome

Contact List

Sumio Ohtsuki
lab head
Sumio Ohtsuki
contact affiliation	Kumamoto University
dataset submitter

Full Dataset Link List

jPOST dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST000349/

jPOST dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST000349/