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PXD007548-4

PXD007548 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleQuantitative Proteomic Analysis of Brucella abortus under Multiple Environmental Stresses
DescriptionWe have used a multiple-environmental-stress strategy to reveal global metabolic adaptations of B. abortus to intravacuolar environmental conditions. These conditions included: (i) a Control condition (growth on TSB, condition #1); (ii) seven single-stress conditions: (condition #2-8) and (iii) a multi-stress condition (#9). The multi-stress was a combination of each single-stress that may better simulated the environments that Brucella may occur during the infection of a host. The proteomic analysis identified and quantified in total 2,272 proteins and 74% of the theoretical proteome, which is providing a wide coverage of B. abortus genome. The identification of proteins necessary for stress resistance is crucial to elucidate the infectious process in order to control brucellosis and may provide valuable clues towards discovery of novel therapeutic targets and effective vaccines.
HostingRepositoryjPOST
AnnounceDate2017-08-24
AnnouncementXMLSubmission_2022-09-18_03:46:11.432.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterXiaodong Zai
SpeciesList scientific name: Brucella abortus; NCBI TaxID: 235;
ModificationListS-carboxamidomethyl-L-cysteine; alpha-amino acetylated residue; L-methionine sulfoxide
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02017-08-24 03:58:35ID requested
12017-08-24 03:58:39announced
22018-09-19 00:25:33announcedUpdated CV, FTP location and Modification list.
32021-02-04 17:20:01announced2021-02-04: Updated FTP location.
42022-09-18 03:46:11announced2022-09-18: Updated FTP location.
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Brucella abortus, proteomic, label-free, environmental stress
Contact List
Xiaodong Zai
lab head
Xiaodong Zai
contact affiliationBeijing Institute of Biotechnology
dataset submitter
Full Dataset Link List
jPOST dataset URI
Dataset FTP location
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