PXD004631-2

PXD004631 is an original dataset announced via ProteomeXchange.

Title	Mitochondrial CaMKII phosphoproteome.
Description	Mice overexpressing CaMKII in myocardial mitochondria have dilated cardiomyopathy that appears to be exclusively driven by metabolic defects that lead to reduced ATP production. Phosphoproteomics study of mitochondrial proteins supports the metabolomics data.
HostingRepository	PRIDE
AnnounceDate	2020-07-31
AnnouncementXML	Submission_2020-09-06_22:58:50.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Eleonora Corradini
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	phosphorylated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Elite

Revision	Datetime	Status	ChangeLog Entry
0	2016-07-21 03:50:03	ID requested
1	2020-07-30 22:11:22	announced
⏵ 2	2020-09-06 22:58:52	announced	2020-09-07: Updated publication reference for PubMed record(s): 32887881.

Luczak ED, Wu Y, Granger JM, Joiner MA, Wilson NR, Gupta A, Umapathi P, Murphy KR, Reyes Gaido OE, Sabet A, Corradini E, Tseng WW, Wang Y, Heck AJR, Wei AC, Weiss RG, Anderson ME, Mitochondrial CaMKII causes adverse metabolic reprogramming and dilated cardiomyopathy. Nat Commun, 11(1):4416(2020) [pubmed]

submitter keyword: Heart, mitochondria, TiIMAC, phosphoproteome, LC-MS/MS

Albert J.R. Heck
contact affiliation	Biomolecular mass spectrometry and proteomics group, Utrecht University
contact email	a.j.r.heck@uu.nl
lab head
Eleonora Corradini
contact affiliation	Biomolecular and mass spectrometry group
contact email	e.corradini1@uu.nl
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/07/PXD004631

PRIDE project URI

• PRIDE
  1. PXD004631
     1. Label: PRIDE project
     2. Name: Mitochondrial CaMKII phosphoproteome.