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PXD004631

PXD004631 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMitochondrial CaMKII phosphoproteome.
DescriptionMice overexpressing CaMKII in myocardial mitochondria have dilated cardiomyopathy that appears to be exclusively driven by metabolic defects that lead to reduced ATP production. Phosphoproteomics study of mitochondrial proteins supports the metabolomics data.
HostingRepositoryPRIDE
AnnounceDate2020-07-31
AnnouncementXMLSubmission_2020-09-06_22:58:50.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterEleonora Corradini
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListphosphorylated residue; iodoacetamide derivatized residue
InstrumentLTQ Orbitrap Elite
Dataset History
RevisionDatetimeStatusChangeLog Entry
02016-07-21 03:50:03ID requested
12020-07-30 22:11:22announced
22020-09-06 22:58:52announced2020-09-07: Updated publication reference for PubMed record(s): 32887881.
Publication List
Luczak ED, Wu Y, Granger JM, Joiner MA, Wilson NR, Gupta A, Umapathi P, Murphy KR, Reyes Gaido OE, Sabet A, Corradini E, Tseng WW, Wang Y, Heck AJR, Wei AC, Weiss RG, Anderson ME, Mitochondrial CaMKII causes adverse metabolic reprogramming and dilated cardiomyopathy. Nat Commun, 11(1):4416(2020) [pubmed]
Keyword List
submitter keyword: Heart, mitochondria, TiIMAC, phosphoproteome, LC-MS/MS
Contact List
Albert J.R. Heck
contact affiliationBiomolecular mass spectrometry and proteomics group, Utrecht University
contact emaila.j.r.heck@uu.nl
lab head
Eleonora Corradini
contact affiliationBiomolecular and mass spectrometry group
contact emaile.corradini1@uu.nl
dataset submitter
Full Dataset Link List
Dataset FTP location
PRIDE project URI
Repository Record List
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