PXD004510-1

PXD004510 is an original dataset announced via ProteomeXchange.

Title	Mapping and Quantification of Brain Protein O-GlcNAcylation in Alzheimer’s Disease
Description	Comprehensive, quantitative proteomics analysis of protein O-GlcNAcylation in post-mortem human brains with and without Alzheimer’s using isobaric tandem mass tags labeling, chemoenzymatic photocleavage enrichment and liquid chromatography coupled to mass spectrometry.
HostingRepository	PRIDE
AnnounceDate	2017-09-04
AnnouncementXML	Submission_2017-09-04_05:35:52.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD004510
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Matthew Monroe
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	TMT6plex; Oxidation; AMTzHexNAc2; Carbamidomethyl
Instrument	LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2016-07-04 07:55:41	ID requested
⏵ 1	2017-09-04 05:35:53	announced

Wang S, Yang F, Petyuk VA, Shukla AK, Monroe ME, Gritsenko MA, Rodland KD, Smith RD, Qian WJ, Gong CX, Liu T, Quantitative proteomics identifies altered O-GlcNAcylation of structural, synaptic and memory-associated proteins in Alzheimer's disease. J Pathol, 243(1):78-88(2017) [pubmed]

submitter keyword: O-GlcNAc, Alzheimer's disease, brain

Tao Liu
contact affiliation	Pacific Northwest National Laboratory
contact email	tao.liu@pnnl.gov
lab head
Matthew Monroe
contact affiliation	Biological Separations & Mass Spectrometry
contact email	matthew.monroe@pnnl.gov
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/09/PXD004510

PRIDE project URI

• PRIDE
  1. PXD004510
     1. Label: PRIDE project
     2. Name: Mapping and Quantification of Brain Protein O-GlcNAcylation in Alzheimer’s Disease