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PXD004510 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMapping and Quantification of Brain Protein O-GlcNAcylation in Alzheimer’s Disease
DescriptionComprehensive, quantitative proteomics analysis of protein O-GlcNAcylation in post-mortem human brains with and without Alzheimer’s using isobaric tandem mass tags labeling, chemoenzymatic photocleavage enrichment and liquid chromatography coupled to mass spectrometry.
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterMatthew Monroe
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListTMT6plex; Oxidation; AMTzHexNAc2; Carbamidomethyl
InstrumentLTQ Orbitrap Velos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02016-07-04 07:55:41ID requested
12017-09-04 05:35:53announced
Publication List
Wang S, Yang F, Petyuk VA, Shukla AK, Monroe ME, Gritsenko MA, Rodland KD, Smith RD, Qian WJ, Gong CX, Liu T, Quantitative proteomics identifies altered O-GlcNAcylation of structural, synaptic and memory-associated proteins in Alzheimer's disease. J Pathol, 243(1):78-88(2017) [pubmed]
Keyword List
submitter keyword: O-GlcNAc, Alzheimer's disease, brain
Contact List
Tao Liu
contact affiliationPacific Northwest National Laboratory
contact emailtao.liu@pnnl.gov
lab head
Matthew Monroe
contact affiliationBiological Separations & Mass Spectrometry
contact emailmatthew.monroe@pnnl.gov
dataset submitter
Full Dataset Link List
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PRIDE project URI
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