PXD003647-1
PXD003647 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Bacterial Interactomes: Desulfovibrio vulgaris_TAP_part 1_Orbitrap Data |
Description | Here we present an AP-MS survey of the bacterium Desulfovibrio vulgaris. We have identified 459 high confidence PPIs from D. vulgaris. Compared to the nine published interactomes, our two networks are smaller; are much less highly connected; have significantly lower false discovery rates; and are much more enriched in protein pairs that are encoded in the same operon, have similar functions, and are reproducibly detected in other physical interaction assays. Our work establishes more stringent benchmarks for the properties of protein interactomes and suggests that bona fide PPIs much more frequently involve protein partners that are annotated with similar functions or that can be validated in independent assays than earlier studies suggested. |
HostingRepository | MassIVE |
AnnounceDate | 2016-02-16 |
AnnouncementXML | Submission_2016-02-16_09:39:48.xml |
DigitalObjectIdentifier | |
ReviewLevel | Non peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Witkowska |
SpeciesList | scientific name: Desulfovibrio vulgaris str. Hildenborough; NCBI TaxID: 882; |
ModificationList | No PTMs are included in the dataset |
Instrument | LTQ Orbitrap Velos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2016-02-16 09:39:12 | ID requested | |
⏵ 1 | 2016-02-16 09:39:49 | announced |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: protein-protein interactions, AP-MS, tandem affinity purification, Desulfovibrio vulgaris |
Contact List
Gareth Butland | |
---|---|
lab head | |
Witkowska | |
contact affiliation | UCSF |
contact email | h_ewa_witkowska@yahoo.com |
dataset submitter |
Full Dataset Link List
MassIVE dataset URI |
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000079275 |