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PXD003101

PXD003101 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteome-wide identification of SAPs in an industrial yeast strain
DescriptionMost proteogenomic approaches for mapping single amino acid polymorphisms (SAPs) require construction of a sample-specific database containing protein variants predicted from the next-generation sequencing (NGS) data. We present a new strategy for direct SAP detection without relying on NGS data. Among the 348 putative SAP peptides identified in an industrial yeast strain, 85.6% of SAP sites were validated by genomic sequencing.
HostingRepositoryPRIDE
AnnounceDate2018-04-18
AnnouncementXMLSubmission_2018-04-18_02:03:40.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterGuo Yufeng
SpeciesList scientific name: Saccharomyces cerevisiae (Baker's yeast); NCBI TaxID: 4932;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentTripleTOF 5600
Dataset History
RevisionDatetimeStatusChangeLog Entry
02015-10-23 01:07:58ID requested
12018-04-18 02:03:42announced
Publication List
Xiong Y, Guo Y, Xiao W, Cao Q, Li S, Qi X, Zhang Z, Wang Q, Shui W, An NGS-Independent Strategy for Proteome-Wide Identification of Single Amino Acid Polymorphisms by Mass Spectrometry. Anal Chem, 88(5):2784-91(2016) [pubmed]
Keyword List
curator keyword: Biological
submitter keyword: proteogenomics, SAP, industrial yeast strain
Contact List
Wenqing Shui
contact affiliationTianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences
contact emailshui_wq@tib.cas.cn
lab head
Guo Yufeng
contact affiliationTianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences
contact emailguo_yf@tib.cas.cn
dataset submitter
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Dataset FTP location
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PRIDE project URI
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