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PXD002719-1

PXD002719 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleQuantitative proteomic analysis of duck lung tissue during infection of avian influenza
DescriptionDucks and wild aquatic birds are the natural reservoirs of avian influenza viruses. However, the host proteome response that causes disease in vivo during infection by the highly pathogenic avian influenza (HPAI) H5N1 virus is still not well understood. In the present study, we compared the proteome response in Muscovy duck lung tissue during 3 day of infection with either a highly virulent or an avirulent H5N1 virus. During infection, proteins involved in immune response of neutrophils and size of cells were increased markedly in the lung by the virulent strain, while the avirulent strain evoked a distinct response, characterized by an increase in proteins involved in cell movement, maturation of dendritic cells, adhesion of phagocytes, and immune response of macrophages.
HostingRepositoryPRIDE
AnnounceDate2022-08-22
AnnouncementXMLSubmission_2022-08-22_07:37:26.364.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterming liao
SpeciesList scientific name: Anas platyrhynchos (Domestic duck) (Anas boschas); NCBI TaxID: 8839;
ModificationListiTRAQ4plex-116 reporter+balance reagent acylated residue
InstrumentTripleTOF 5600
Dataset History
RevisionDatetimeStatusChangeLog Entry
02015-08-13 01:04:37ID requested
12022-08-22 07:37:26announced
Publication List
Dataset with its publication pending
Keyword List
curator keyword: Biological, Biomedical
submitter keyword: Duck, Lung tissue, Avian influenza
Contact List
Ming Liao
contact affiliationCollege of Veterinary Medicine, South China Agricultural University, Guangzhou, China
contact emailmliao1968@163.com
lab head
ming liao
contact affiliationsouth china agricultural university
contact emailmliao1968@163.com
dataset submitter
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