PXD000445 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteomic profiling of colorectal adenomas |
Description | Colorectal adenomas are cancer precursor lesions of the large bowel. In these preinvasive lesions, a vast array of genomic and epigenomic changes have been detailed, but the consequence of these molecular alterations on the effectors of biological function (proteins) has not been comprehensively explored. |
HostingRepository | PRIDE |
AnnounceDate | 2014-07-24 |
AnnouncementXML | Submission_2014-07-24_05:15:33.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD000445 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Anuli Uzozie |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | iTRAQ8plex-114 reporter+balance reagent O4'-acylated tyrosine; monohydroxylated residue; iTRAQ8plex-116 reporter+balance reagent acylated residue; iTRAQ8plex-114 reporter+balance reagent N6-acylated lysine; iTRAQ8plex-114 reporter+balance reagent acylated N-terminal; methylthiolated residue |
Instrument | instrument model: LTQ Orbitrap Velos; LTQ Orbitrap Velos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2013-09-03 05:52:23 | ID requested | |
1 | 2014-04-03 07:28:28 | announced | |
⏵ 2 | 2014-07-24 05:15:34 | announced | Updated project metadata. |
Publication List
Uzozie A, Nanni P, Staiano T, Grossmann J, Barkow-Oesterreicher S, Shay JW, Tiwari A, Buffoli F, Laczko E, Marra G, Sorbitol dehydrogenase overexpression and other aspects of dysregulated protein expression in human precancerous colorectal neoplasms: a quantitative proteomics study. Mol Cell Proteomics, 13(5):1198-218(2014) [pubmed] |
Keyword List
curator keyword: Biomedical, Highlighted |
submitter keyword: adenoma, proteomics, iTRAQ 8-plex |
Contact List
PD Dr. Giancarlo Marra |
contact affiliation | Institute of Molecular Cancer Research, University of Zurich, Switzerland |
contact email | marra@imcr.uzh.ch |
lab head | |
Anuli Uzozie |
contact affiliation | University of Zurich |
contact email | uzozie.anuli@imcr.uzh.ch |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2014/04/PXD000445 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD000445
- Label: PRIDE project
- Name: Proteomic profiling of colorectal adenomas