PXD000445

PXD000445 is an original dataset announced via ProteomeXchange.

Title	Proteomic profiling of colorectal adenomas
Description	Colorectal adenomas are cancer precursor lesions of the large bowel. In these preinvasive lesions, a vast array of genomic and epigenomic changes have been detailed, but the consequence of these molecular alterations on the effectors of biological function (proteins) has not been comprehensively explored.
HostingRepository	PRIDE
AnnounceDate	2014-07-24
AnnouncementXML	Submission_2014-07-24_05:15:33.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD000445
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Anuli Uzozie
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iTRAQ8plex-114 reporter+balance reagent O4'-acylated tyrosine; monohydroxylated residue; iTRAQ8plex-116 reporter+balance reagent acylated residue; iTRAQ8plex-114 reporter+balance reagent N6-acylated lysine; iTRAQ8plex-114 reporter+balance reagent acylated N-terminal; methylthiolated residue
Instrument	instrument model: LTQ Orbitrap Velos; LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2013-09-03 05:52:23	ID requested
1	2014-04-03 07:28:28	announced
⏵ 2	2014-07-24 05:15:34	announced	Updated project metadata.

Uzozie A, Nanni P, Staiano T, Grossmann J, Barkow-Oesterreicher S, Shay JW, Tiwari A, Buffoli F, Laczko E, Marra G, Sorbitol dehydrogenase overexpression and other aspects of dysregulated protein expression in human precancerous colorectal neoplasms: a quantitative proteomics study. Mol Cell Proteomics, 13(5):1198-218(2014) [pubmed]

curator keyword: Biomedical, Highlighted

submitter keyword: adenoma, proteomics, iTRAQ 8-plex

PD Dr. Giancarlo Marra
contact affiliation	Institute of Molecular Cancer Research, University of Zurich, Switzerland
contact email	marra@imcr.uzh.ch
lab head
Anuli Uzozie
contact affiliation	University of Zurich
contact email	uzozie.anuli@imcr.uzh.ch
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2014/04/PXD000445

PRIDE project URI

• PRIDE
  1. PXD000445
     1. Label: PRIDE project
     2. Name: Proteomic profiling of colorectal adenomas