PXD000327-2

PXD000327 is an original dataset announced via ProteomeXchange.

Title	Quantitative proteomic profiling reveals novel region-specific markers in the adult mouse brain
Description	Here we present the data obtained from a high precision 18O-labeling strategy used to quantitatively map membrane proteins isolated from myelin-enriched fractions purified from distinct brain regions of an adult mouse. To this end, we present an updated catalog of myelin-associated proteins found in the vertebrate CNS with relevance for investigations of myelin disorders. We also present a number of regiospecific protein markers of the brain, many of which remain unannotated in current online brain mapping databases.
HostingRepository	PRIDE
AnnounceDate	2014-07-25
AnnouncementXML	Submission_2014-07-25_01:20:48.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	L Dagley
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue; (18)O label at both C-terminal oxygens
Instrument	LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2013-07-08 02:27:47	ID requested
1	2013-11-22 03:28:25	announced
1	2013-11-22 05:19:36	announced
⏵ 2	2014-07-25 01:20:48	announced	Updated project metadata.
3	2014-08-08 01:53:34	announced	Updated project metadata.

Dataset with its publication pending

submitter keyword: 18O-based stable isotope labeling, mass spectrometry, membrane proteins, myelin interactome, quantitative proteomics

L Dagley
contact affiliation	Department of Biochemistry and Molecular Biology
contact email	l.gianni@student.unimelb.edu.au
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2013/11/PXD000327

PRIDE project URI

• PRIDE
  1. PXD000327
     1. Label: PRIDE project
     2. Name: Quantitative proteomic profiling reveals novel region-specific markers in the adult mouse brain