PXD075165

PXD075165 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Alpibectir–Ethionamide combination (AlpE) for the treatment of tuberculosis
Description	MS/MS data for profiling of Mycobacterium tuberculosis treated with Compound 1, Compound 2, Alpibectir, Compound 3 and vehicle control: 10 samples were analyzed in parallel (TMT 10-plex) to generate whole proteome profiling data. Mycobacterium tuberculosis were treated for 72h with 1µM of the respective compound: Samples 1 and 2 treated with Compound 1, samples 3 and 4 with Compound 2, samples 5 and 6 with Alpibectir, samples 7 and 8 with Compound 3 and samples 9 and 10 with DMSO (vehicle control experiments n=1 and n=2).
HostingRepository	PRIDE
AnnounceDate	2026-04-02
AnnouncementXML	Submission_2026-04-01_23:20:30.597.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sascha Knecht
SpeciesList	scientific name: Mycobacterium tuberculosis H37Rv; NCBI TaxID: NEWT:83332;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue; methionine oxidation with neutral loss of 64 Da; acetylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2026-03-03 15:10:57	ID requested
⏵ 1	2026-04-01 23:20:31	announced

Publication List

10.1038/S41467-026-71460-6;

10.1038/S41467-026-71460-6;

Keyword List

submitter keyword: None

submitter keyword: None

Contact List

Thilo Werner
contact affiliation	Target Discovery, GSK / Cellzome
contact email	thilo.x.werner@gsk.com
lab head
Sascha Knecht
contact affiliation	Target Discovery, GSK / Cellzome
contact email	sascha.knecht@me.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/04/PXD075165
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/04/PXD075165

PRIDE project URI

Repository Record List

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