PXD072382
PXD072382 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Cardiomyocyte-derived GPX4 stabilizes BNIP3 to facilitate mitophagy and mitigate myocardial ischemia/reperfusion injury |
| Description | To elucidate the molecular mechanisms by which GPX4 regulates mitochondrial function, we overexpressed GPX4 in cardiomyocytes and subjected them to hypoxia-reoxygenation (H/R) modeling. Co-immunoprecipitation (Co-IP) coupled with liquid chromatography-tandem mass spectrometry (LC-MS/MS) was employed to identify potential partners of GPX4. |
| HostingRepository | iProX |
| AnnounceDate | 2025-12-22 |
| AnnouncementXML | Submission_2025-12-23_19:15:06.124.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Lingfeng Zhong |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | LTQ |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-12-23 19:14:43 | ID requested | |
| ⏵ 1 | 2025-12-23 19:15:06 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Cardiomyocytes, GPX4, BNIP3, Mitophagy |
Contact List
| Bozhi Ye | |
|---|---|
| contact affiliation | Wenzhou Medical University |
| contact email | fredye2012@163.com |
| lab head | |
| Lingfeng Zhong | |
| contact affiliation | Zhejiang University |
| contact email | zhonglf@zju.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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