⮝ Full datasets listing
PXD070687
PXD070687 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Systematic and Quantitative Investigation of Newly Synthesized Proteins Reveals Distinct Ion Homeostasis and Mitochondrial Changes between Cuproptosis and Ferroptosis in Human Cells |
| Description | To better understand ferroptosis and cuproptosis, here we systematically and quantitatively analyzed newly synthesized proteins (NSPs), which reflect rapid changes in gene expression during cell death without the interference from the existing proteins. Integrating metabolic labeling with multiplexed proteomics, the results revealed that both types of cell death shared some common features, such as mitochondrial disorder and gene expression suppression. Furthermore, different changes between them were also found. |
| HostingRepository | MassIVE |
| AnnounceDate | 2026-03-10 |
| AnnouncementXML | Submission_2026-03-10_07:19:17.504.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Non peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Supported dataset by repository |
| PrimarySubmitter | Yue Wu |
| SpeciesList | scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606; |
| ModificationList | unknown modification; unknown modification |
| Instrument | Orbitrap Exploris 480 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-11-13 06:50:45 | ID requested | |
| ⏵ 1 | 2026-03-10 07:19:18 | announced |
Publication List
| no publication |
Keyword List
| submitter keyword: bioorthogonal chemistry, multiplexed proteomics, newly synthesized proteins, cuproptosis, ferroptosis, DatasetType:Proteomics |
Contact List
| Ronghu Wu | |
|---|---|
| contact affiliation | Georgia Institute of Technology |
| contact email | ronghu.wu@chemistry.gatech.edu |
| lab head | |
| Yue Wu | |
| contact affiliation | Georgia Institute of Technology |
| contact email | ywu3090@gatech.edu |
| dataset submitter | |
Full Dataset Link List
| MassIVE dataset URI |
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive-ftp.ucsd.edu/v11/MSV000099889/ |
