PXD069285 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Label free quantification approach comparing hepatic tissue from SCD and healthy mice |
| Description | Sickle cell disease (SCD) is characterized by the expression of an abnormal hemoglobin variant (HbS) that promotes distortion and early destruction of red blood cells, resulting in hemolytic anemia, vaso-occlusive crisis, ischemia and, ultimately, tissue damage. Hepatic function is specially compromised in SCD patients; however, the underlying pathological mechanisms remain largely unknown. In the current study, through a label free quantitative proteomic approach, we identified significant alterations in protein expression compared to healthy controls. These changes unveiled distinct proteome expression profiles between groups. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-03-10 |
| AnnouncementXML | Submission_2026-03-10_04:10:09.149.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Lucía Beltrán-Camacho |
| SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | timsTOF fleX |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-10-10 00:40:24 | ID requested | |
| ⏵ 1 | 2026-03-10 04:10:09 | announced | |
Publication List
Keyword List
| submitter keyword: Liver, mice, sickle cell diasease |
Contact List
| Lucía Beltrán Camacho |
|---|
| contact affiliation | University of Córdoba |
| contact email | belcamlucia@gmail.com |
| lab head | |
| Lucía Beltrán-Camacho |
|---|
| contact affiliation | University of Cádiz
Institute of Biomediccal Research of Cádiz |
| contact email | belcamlucia@gmail.com |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/03/PXD069285 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD069285
- Label: PRIDE project
- Name: Label free quantification approach comparing hepatic tissue from SCD and healthy mice
