PXD065737 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Phytotoxic peptides released by the phytopathogenic fungus Botrytis cinerea as a potential novel mechanism of fungal infection |
| Description | Botrytis cinerea, the causal agent of gray mold and noble rot, is a phytopathogenic fungus with a scientific and economic relevance due to its effects in agriculture. This fungus employs various molecular tools, such as enzymes and secondary metabolites, to infect and colonize plant tissues. Pathogenicity and virulence factors are identified, highlighting their role in the infectious cycle. Our approach presents the description of a new infection mechanism in the phytopathogenic fungus Botrytis cinerea, based on the production of bioactive peptides. Those peptides were isolated from cultures with glucose (constitutive stage) and tomato (virulence inductor), and showed significant effects on virulence, suggesting a crucial function in the fungus-plant interaction. Biochemical and genetic analysis methods were employed to determine the expression of genes involved in peptide production, highlighting the potential for de novo peptide synthesis and degradation of parental proteins. The results indicate that B. cinerea has significant biotechnological potential, as it can generate peptides of interest for industrial and pharmaceutical applications. This work is pioneering in describing the peptidome of a phytopathogenic fungus and suggests new strategies for controlling microbial infections. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-06-04 |
| AnnouncementXML | Submission_2026-06-04_13:07:27.760.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | ALMUDENA ESCOBAR NIÑO |
| SpeciesList | scientific name: Botryotinia fuckeliana (strain B05.10) (Noble rot fungus) (Botrytis cinerea); NCBI TaxID: NEWT:332648; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Exploris 240 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-07-03 06:37:41 | ID requested | |
| ⏵ 1 | 2026-06-04 13:07:28 | announced | |
Publication List
Keyword List
| submitter keyword: Botrytis cinerea, bioactive peptides, new phytotoxic tool, peptidome, LC-MS/MS |
Contact List
| Francisco Javier Fernández Acero |
|---|
| contact affiliation | University of Cadiz |
| contact email | franciscojavier.fernandez@gm.uca.es |
| lab head | |
| ALMUDENA ESCOBAR NIÑO |
|---|
| contact affiliation | University of Cadiz |
| contact email | almudena.escobar@uca.es |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
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| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD065737
- Label: PRIDE project
- Name: Phytotoxic peptides released by the phytopathogenic fungus Botrytis cinerea as a potential novel mechanism of fungal infection
