PXD065033

PXD065033 is an original dataset announced via ProteomeXchange.

Title	BAFFR interactome in mouse B cells
Description	In this study, we have used affinity purification coupled with quantitative mass spectrometry to analyse the BAFFR interactome in mouse LPS-activated B cells. To do this, we used primary B cells from mice expressing endogenous BAFFR with a C-terminal Twin-StrepTag. By AP-MS, we identified TACI as a BAFF-stimulation-induced BAFFR interactor.
HostingRepository	PRIDE
AnnounceDate	2026-04-01
AnnouncementXML	Submission_2026-04-01_15:26:10.668.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Daisy Luff
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090;
ModificationList	ubiquitination signature dipeptidyl lysine; acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2025-06-15 16:05:35	ID requested
⏵ 1	2026-04-01 15:26:11	announced

10.1084/JEM.20251308;

submitter keyword: StrepTag, AP-MS,BAFFR, Tnfrsf13c, TACI, nLC-MS/MS, mouse, B-cells, BAFF, interactome

Victor Tybulewicz
contact affiliation	The Francis Crick Institute
contact email	Victor.T@crick.ac.uk
lab head
Daisy Luff
contact affiliation	The Francis Crick Institute, London, UK
contact email	daisy.luff@crick.ac.uk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/04/PXD065033

PRIDE project URI

• PRIDE
  1. PXD065033
     1. Label: PRIDE project
     2. Name: BAFFR interactome in mouse B cells