Human resting and activated T lymphoblast (LT CTRL and LT ACT) centrosome-enriched subcellular fractions from LT CTRL and LT ACT were prepared as analysed by multiplexed quantitative proteomics and LC-MS/MS. Samples from different donors were pooled after first lysis. For further details, refer to reference (Martin-Cofreces NB, Chichon FJ, Calvo E, et al. The chaperonin CCT controls T cell receptor- driven 3D configuration of centrioles. Sci Adv. 2020;6(49):eabb7242).