PXD047310 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Compound-centric chemical proteomics to screen fructose binding proteins |
| Description | To identify protein targets of fructose, we performed a compound-centric chemical proteomics (CCCP) experiment on podocytes with P-fructose. Briefly, podocytes were incubated with P-fructose, and the cellular proteins that directly bind to fructose were covalently crosslinked to P-fructose by UV irradiation. After orthogonal conjugation was achieved with azide-biotin via click chemistry and affinity purification was performed, the P-fructose-enriched proteins were analyzed by liquid chromatography coupled with tandem mass spectrometry (LC‒MS/MS). |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-06-05 |
| AnnouncementXML | Submission_2026-06-05_00:49:33.971.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Jingzi Zhang |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | TripleTOF 5600 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2023-11-27 23:40:08 | ID requested | |
| ⏵ 1 | 2026-06-05 00:49:34 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: chemoproteomics, small molecule-protein interaction,fructose |
Contact List
| Jingzi Zhang |
|---|
| contact affiliation | Nanjing University |
| contact email | zhangjingzi@nju.edu.cn |
| lab head | |
| Jingzi Zhang |
|---|
| contact affiliation | Medical School of Nanjing University |
| contact email | zhangjingzi@nju.edu.cn |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
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| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD047310
- Label: PRIDE project
- Name: Compound-centric chemical proteomics to screen fructose binding proteins
