PXD045783 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | The ISG Atlas: A Loss-Of-Function Analysis Characterizes Antiviral Properties of Interferon Stimulated Genes |
| Description | The innate immune system requires the activity of interferon-stimulated genes (ISGs) to mount its protective response against viruses and other pathogens. However, the sensitivity of ISGs against viruses varies widely, and the spectrum of antiviral activities of ISGs is only partially understood. Utilizing an arrayed, time-resolved loss-of-function screen, we systematically investigated 285 ISGs for their virus-modulating activity against eight viruses. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-03-10 |
| AnnouncementXML | Submission_2026-03-10_02:31:57.631.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Sabri Hamad |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2023-09-28 09:28:59 | ID requested | |
| ⏵ 1 | 2026-03-10 02:31:58 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Viral replication, Live-cell imaging, SARS-CoV-2,Innate immune system, Interferon-stimulated genes (ISGs), Arrayed knock-out screen, Proteomics |
Contact List
| Andreas Pichlmair |
|---|
| contact affiliation | Technical University Munich, Faculty of Medicine, Institute of Virology, Viral Immunopathology, Schneckenburger Str. 8, D-81675 Munich, Germany |
| contact email | andreas.pichlmair@tum.de |
| lab head | |
| Sabri Hamad |
|---|
| contact affiliation | Technical University of Munich |
| contact email | sabri.hamad@tum.de |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/03/PXD045783 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD045783
- Label: PRIDE project
- Name: The ISG Atlas: A Loss-Of-Function Analysis Characterizes Antiviral Properties of Interferon Stimulated Genes
