To identify potential cellular RNA-binding proteins (RBPs) that interact with the FSE RNA of SARS-CoV-2, biotinylated in vitro transcription (IVT) FSE RNA from the SARS-CoV-2 genome was incubated with lysates of H460 cells infected with human coronavirus OC43 (HCoV-OC43) and Huh7 cells infected with human coronavirus 229E (HCoV-229E). To exclude non-specific binders, a non-related RNA was used as a control.