Lysine and arginine methylation are fundamental post-translational modifications (PTMs) that can regulate biological processes such as chromatin dynamics, transcriptional activity, and cellular signaling, with misregulation implicated in cancer and neurodevelopmental disorders. While advances in mass spectrometry (MS)-based proteomics have enabled proteome-wide mapping of methylation sites, the confident detection and localization of these modifications remains challenging. In this study, we have reanalyzed publicly available human methylation-enriched datasets using a standardized computational pipeline, to generate a high-confidence atlas of human methylation. Our workflow integrates database searching via the Trans-Proteomic Pipeline with a decoy-based statistical method for the independent estimation of false localization rates. This process yielded a high-confidence Human Methylation Atlas of 1,858 sites (87 methyl-lysine, 1,771 methyl-arginine) across 1,068 proteins, classified into Gold, Silver, and Bronze confidence tiers.