In our study, seven plasma proteomics methods were evaluated including five MS-based protocols (Neat (Untreated), TOP14 depletion (Thermo Scientific), Enrich (PreOmics, part of Bruker now), PCA-N (Mann’s protocol + ref) and Proteograph XT (Seer)) and two antibody-based ones (Olink Target Inflammation and Olink Reveal (Olink, part of Thermo Scientific now), according to the manufacturer’s instructions