Rewilding of animals holds promise for restoring industrialized microbiomes back to their ancestral state, enhancing resilience and reducing the requirement for therapeutic interventions. Using a “two-eyed seeing” approach we studied the Muus Muus, a herd of rewilded cattle in the traditional territory of the Tla-o-qui-aht Peoples on Meares Island. These cattle have a browser-grazer lifestyle, foraging on old growth forest plants, native grasses, and seaweeds, reminiscent of their extinct ancestor, the auroch. Using high-resolution, multi-layered omics and trnL-P6 sequencing we confirmed digestion of unconventional forages, including salal, cedar, and green seaweed. The resistome of the rewilded cattle displayed significantly less abundant AMR genes, offering a glimpse into the profiles of non-selected ruminant microbiomes and presenting new opportunities to mitigate the prevailing AMR crisis.