PXD065072-1
PXD065072 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Multi-omics profiling of Parkinson’s disease mouse models reveals region-specific molecular alterations |
| Description | We conducted proteomic and phosphoproteomic profiling of two widely used Parkinson’s disease (PD) mouse models: the neurotoxin-based MPTP model and the α-synuclein preformed fibril (PFF) inoculation model. Tissues from substantia nigra and cerebellum were collected for multi-omics analysis to uncover region-specific protein expression and phosphorylation changes associated with PD pathogenesis. |
| HostingRepository | iProX |
| AnnounceDate | 2025-06-16 |
| AnnouncementXML | Submission_2025-06-16_19:34:34.744.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Xinhe Huang |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | phosphorylated residue |
| Instrument | Q Exactive HF-X |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-06-16 19:34:21 | ID requested | |
| ⏵ 1 | 2025-06-16 19:34:35 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Parkinson’s disease, phosphoproteomics, proteomics, substantia nigra, cerebellum, mouse model, MPTP, α-synuclein PFF |
Contact List
| Yu Xue | |
|---|---|
| contact affiliation | Huazhong University of Science and Technology |
| contact email | xueyu@mail.hust.edu.cn |
| lab head | |
| Xinhe Huang | |
| contact affiliation | Huazhong University of Science and Technology |
| contact email | hxhdddh2@gmail.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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