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PXD064145

PXD064145 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleImpact of clozapine and risperidone on the proteome of the rat prefrontal cortex (PFC) and remaining cortex (CX)
DescriptionThis study investigates the molecular mechanisms of action of clozapine and risperidone in the rat brain, specifically targeting the prefrontal cortex (PFC) and the remaining cortical regions (CX). A multi-platform proteomic approach was employed to capture comprehensive changes in protein expression induced by chronic (21 days) antipsychotic drug treatment.
HostingRepositoryMassIVE
AnnounceDate2025-05-21
AnnouncementXMLSubmission_2025-05-21_23:14:13.228.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterPatrycja Sarga
SpeciesList scientific name: Mus musculus; common name: house mouse; NCBI TaxID: 10090; scientific name: Rattus norvegicus; common name: Norway rat; NCBI TaxID: 10116;
ModificationListOxidation; Acetyl; CarbamidomethylDTT
InstrumentOrbitrap Astral; Q Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-05-21 05:26:44ID requested
12025-05-21 23:14:13announced
Publication List
no publication
Keyword List
submitter keyword: rat PFC, rat CX, clozapine, riperidone, LC-MS/MS, DatasetType:Proteomics
Contact List
Sylwia Kedracka-Krok
contact affiliationDepartment of Physical Biochemistry, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland
contact emailsylwia.kedracka-krok@uj.edu.pl
lab head
Patrycja Sarga
contact affiliationJagiellonian University
contact emailpatrycja.sarga@uj.edu.pl
dataset submitter
Full Dataset Link List
MassIVE dataset URI
Dataset FTP location
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