PXD063405

PXD063405 is an original dataset announced via ProteomeXchange.

Title	Protein composition in ancient wheats is determined by ploidy level
Description	Gluten and amylase/trypsin-inhibitors (ATIs) are known triggers for wheat-related disorders. Ancient wheat species like einkorn, emmer, Khorasan wheat, Polish wheat and spelt are suggested to have fewer of these immunoreactive proteins compared to modern common wheat, because breeding for higher yields and increased resistance to plant diseases might have resulted in changes in the protein composition. Currently, there are only very few studies on the protein composition of ancient wheat species. This comparative study investigated the bread volume, protein content as well as gluten and ATI content and composition, along with the inhibitory activity in ten ancient wheat varieties cultivated under organic conditions. The varieties had different ploidy levels and were harvested in three consecutive years. The various analyses consistently concluded that differences in protein composition were associated with the different ploidy levels. This means that the results were similar for the diploid species (einkorn), the tetraploid species (emmer, durum wheat, Khorasan wheat and Polish wheat) and for the hexaploid species (spelt and common wheat), respectively. These results suggest that breeding has likely not increased the immunoreactive potential of wheat and ancient wheats are unlikely to provide improved tolerability for individuals with wheat-related disorders.
HostingRepository	PanoramaPublic
AnnounceDate	2025-04-28
AnnouncementXML	Submission_2025-04-28_10:39:05.929.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Nora Jahn
SpeciesList	scientific name: Triticum spelta; NCBI TaxID: 58933; scientific name: Triticum turgidum subsp. durum; NCBI TaxID: 4567; scientific name: Triticum monococcum; NCBI TaxID: 4568;
ModificationList	Gln->pyro-Glu; Carbamidomethyl; Label:13C(6)15N(2); Label:13C(6)15N(4); Label:13C(5)15N(1); Label:13C(2)15N(1)
Instrument	Q Exactive Plus

Revision	Datetime	Status	ChangeLog Entry
0	2025-04-28 10:30:23	ID requested
⏵ 1	2025-04-28 10:39:06	announced

no publication

submitter keyword: Amylase/trypsin-inhibitors, gliadin, gluten, wheat-related disorders

Katharina Scherf
contact affiliation	Leibniz Institute for Food Systems Biology at the Technical University of Munich
contact email	k.scherf.leibniz-lsb@tum.de
lab head
Nora Jahn
contact affiliation	Karlsruhe Institute of Technology
contact email	nora.jahn@kit.edu
dataset submitter

Panorama Public dataset URI