This research project aims to explore the multiomics landscape of plasma exosomes in patients with schizophrenia. Our study involves 10 first-episode drug-naïve schizophrenia patients and 10 healthy controls. By comparing the exosomes derived from these two groups, we hope to uncover biomarkers associated with schizophrenia and potential pathogenic mechanisms. The project seeks to provide new insights for the early diagnosis and intervention of schizophrenia.