PXD060528
PXD060528 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Amylase/trypsin-inhibitor content and inhibitory activity of German common wheat landraces and modern varieties do not differ |
| Description | Amylase/trypsin-inhibitors (ATIs) are triggers for wheat-related disorders like baker’s asthma and nonceliac wheat sensitivity. With the rise ofwheat-related disordersamong the population, the hypothesis that breeding may have resulted in changes in the protein composition of wheat was put forward. The ATI content of 14 German common wheat landraces and six modern varieties harvested in three consecutive years was analyzed by liquid chromatography–tandem mass spectrometry, and the inhibitory activity against α-amylase was measured with an enzymatic assay. The mean ATI content and proportion of crude protein of both groups did not differ. There were also only small differences in the content and proportion of single ATIs. The mean values for the inhibitory activity of both groups were also similar. These results indicate that breeding might not have led to changes in the protein composition and landraces are unlikely to be better tolerated than modern varieties. |
| HostingRepository | PanoramaPublic |
| AnnounceDate | 2025-02-08 |
| AnnouncementXML | Submission_2025-02-08_19:59:55.480.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Non peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Supported dataset by repository |
| PrimarySubmitter | Nora Jahn |
| SpeciesList | scientific name: Triticum aestivum; NCBI TaxID: 4565; |
| ModificationList | Gln->pyro-Glu; Carbamidomethyl; Label:13C(6)15N(2); Label:13C(6)15N(4); Label:13C(5)15N(1); Label:13C(2)15N(1) |
| Instrument | Q Exactive Plus |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-02-05 14:48:44 | ID requested | |
| ⏵ 1 | 2025-02-08 19:59:55 | announced |
Publication List
| no publication |
Keyword List
| submitter keyword: Amylase/trypsin inhibitors, non-celiac wheat sensitivity, landraces, old varieties |
Contact List
| Katharina Scherf | |
|---|---|
| contact affiliation | Leibniz Institute for Food Systems Biology at the Technical University of Munich |
| contact email | k.scherf.leibniz-lsb@tum.de |
| lab head | |
| Nora Jahn | |
| contact affiliation | Karlsruhe Institute of Technology |
| contact email | nora.jahn@kit.edu |
| dataset submitter | |
Full Dataset Link List
| Panorama Public dataset URI |
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