PXD059419

PXD059419 is an original dataset announced via ProteomeXchange.

Title	Effects of DINCH and MINCH exposure on the proteome of differentiating primary human stromal vascular fraction cells
Description	Here, we evaluated the molecular effects of 10 nM and 10 µM DINCH and MINCH exposure on the proteome profiles of differentiating human primary SVF cells. The SVF cells derived from the subcutaneous adipose tissue of donors undergoing aesthetic surgery at abdomen, leg or back. The dataset comprised male and female donors.
HostingRepository	PRIDE
AnnounceDate	2025-08-05
AnnouncementXML	Submission_2025-08-05_04:41:24.757.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Alix Sarah Aldehoff
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive HF; Spectronaut

Revision	Datetime	Status	ChangeLog Entry
0	2025-01-03 05:53:13	ID requested
⏵ 1	2025-08-05 04:41:25	announced

10.1021/acs.est.5c01206;

Aldehoff AS, Karkossa I, Broghammer H, Krupka S, Weiner J, Goerdeler C, Nuwayhid R, Langer S, Wabitsch M, Rolle-Kampczyk U, Kl, ö, ting N, Bl, ü, her M, Heiker JT, von Bergen M, Schubert K, Advanced Proteomics Approaches Hold Potential for the Risk Assessment of Metabolism-Disrupting Chemicals as Omics-Based NAM: A Case Study Using the Phthalate Substitute DINCH. Environ Sci Technol, 59(31):16193-16216(2025) [pubmed]

submitter keyword: Human stromal vascular fraction, adipogenesis, DINCH, subcutaneous adipose tissue, MINCH

Kristin Schubert
contact affiliation	Helmholtz-Centre for Environmental Research - UFZ, Department of Molecular Toxicology
contact email	kristin.schubert@ufz.de
lab head
Alix Sarah Aldehoff
contact affiliation	Helmholtz-Centre for Environmental Research UFZ GmbH
contact email	alix-sarah.aldehoff@ufz.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/08/PXD059419

PRIDE project URI

• PRIDE
  1. PXD059419
     1. Label: PRIDE project
     2. Name: Effects of DINCH and MINCH exposure on the proteome of differentiating primary human stromal vascular fraction cells