PXD058887

PXD058887 is an original dataset announced via ProteomeXchange.

Title	Integrated proteomics and metabolomic analyses reveal the accumulation mechanism of bioactive components in Polygonatum odoratum
Description	Polygonatum odoratum (MILL.) DRUCE is rich in bioactive components with high medicinal value. To maximize the clinical benefits, it is of great significance to efficiently extract key bioactive components from appropriate growth stages in which they are most abundant. In this study, we analyzed the changes of metabolite accumulation and protein expression in P. odoratum rhizomes at different growth stages using targeted metabolomics combined with proteomics, and identified a total of 1,237 differentially abundant metabolites (DAMs). Flavonoids accumulated most in winter, and the biosynthesis pathways associated with flavonoids, isoflavonoids, flavones and flavonols exhibited significant differentially expressed proteins (DEPs). Among them, PGT, FLS, CYP75B1, HIDH, IF7MAT, and UFT73C6 were positively correlated with flavonoid accumulation. Steroid saponins accumulated most in spring, and the biosynthetic pathways of steroid and brassinosteroid biosynthesis exhibited DEPs. Among them, FDFT1, TM7SF2, DHCR7, CAS1
HostingRepository	iProX
AnnounceDate	2024-12-14
AnnouncementXML	Submission_2024-12-15_22:37:32.043.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yifan Zhu
SpeciesList	scientific name: Polygonatum odoratum; NCBI TaxID: 82207;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF SCP

Revision	Datetime	Status	ChangeLog Entry
0	2024-12-15 22:37:09	ID requested
⏵ 1	2024-12-15 22:37:32	announced

Dataset with its publication pending

submitter keyword: Polygonatum odoratum, steroidal saponins, flavonoids, metabolome, proteome

Shuang Liang
contact affiliation	Zhejiang Sci-Tech University
contact email	202120801050@mails.zstu.edu.cn
lab head
Yifan Zhu
contact affiliation	Zhejiang Sci-Tech University
contact email	zdnlzyf@163.com
dataset submitter

iProX dataset URI