PXD058819

PXD058819 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	TMT proteomics of Cmtr1 cKO naive CD4 T cells
Description	We aim to find the gene-specific effects of Cmtr1 KO in mouse CD4 T cells. TMT proteomics datasets were generated to find out which proteins are dependent on Cmtr1 for their expression.
HostingRepository	PRIDE
AnnounceDate	2025-10-16
AnnouncementXML	Submission_2025-10-16_07:07:41.071.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Alison Galloway
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-12-12 10:17:29	ID requested
⏵ 1	2025-10-16 07:07:42	announced

Publication List

10.1016/j.celrep.2025.116412;
Galloway A, Knop K, Gomez-Moreira C, Xavier V, Thomson S, Yoshikawa H, Suska O, Lukoszek R, Kaskar A, Lamond AI, MacVicar T, Cowling VH, CMTR1 directs mitochondrial dynamics during T cell activation through epitranscriptomic regulation of splice isoforms. Cell Rep, 44(10):116412(2025) [pubmed]

10.1016/j.celrep.2025.116412;

Galloway A, Knop K, Gomez-Moreira C, Xavier V, Thomson S, Yoshikawa H, Suska O, Lukoszek R, Kaskar A, Lamond AI, MacVicar T, Cowling VH, CMTR1 directs mitochondrial dynamics during T cell activation through epitranscriptomic regulation of splice isoforms. Cell Rep, 44(10):116412(2025) [pubmed]

Keyword List

submitter keyword: T cell lymphocyte Cmtr1 RNA cap

submitter keyword: T cell lymphocyte Cmtr1 RNA cap

Contact List

Victoria H. Cowling
contact affiliation	Cancer Research UK Scotland Institute, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow G61 1QH, UK
contact email	Victoria.Cowling@glasgow.ac.uk
lab head
Alison Galloway
contact affiliation	CRUK Scotland Institute
contact email	a.galloway@crukscotlandinstitute.ac.uk
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/10/PXD058819
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/10/PXD058819

PRIDE project URI

Repository Record List

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