PXD057735

PXD057735 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Identification of substrates of ZDHHC19 in mouse haploid spermatids using Acyl RAC
Description	Reversible palmitoylation is catalyzed by palmitoyltransferase(PAT) from the zinc-finger DHHC domain-containing protein (ZDHHC) family. The Zdhhc19 knockout male mice showed infertility and Zdhhc19 deficient sperm showed severe morphological defects. To identify the candidate substrates of ZDHHC19 in haploid spermatids, we carried out label free mass spectrometry (MS) combined with resin-assisted capture (RAC) methods. This study reveals the role of palmitoylation mediated by ZDHHC19 during spermiogenesis.
HostingRepository	PRIDE
AnnounceDate	2025-09-10
AnnouncementXML	Submission_2025-09-10_05:30:40.549.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jiaoyang Li
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-11-11 00:41:04	ID requested
⏵ 1	2025-09-10 05:30:41	announced

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: spermiogenesis
ZDHHC19
palmitoylation

submitter keyword: spermiogenesis

ZDHHC19

palmitoylation

Contact List

Ruibao Ren
contact affiliation	Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
contact email	rbren@sjtu.edu.cn
lab head
Jiaoyang Li
contact affiliation	Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
contact email	lejuyoung@163.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/09/PXD057735
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/09/PXD057735

PRIDE project URI

Repository Record List

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