Archaeological remains covered with concretions, including human bones, are commonly found in certain areas and time periods of interest for understanding the past, but have yet to be investigated for potential ancient DNA (aDNA) and protein content. We extracted aDNA and proteins in tandem from human dental remains and the concretions surrounding them and compared them to non-concreted human dental remains from the same site. Concretions appeared homogeneous in colour and texture, consisting of a hard dark grey sediment adhered to the bone surfaces, presumably as a result of cyclical waterlogging of the burial deposits as well as postcranial human remains from a contemporary site. Concretions were found to contain human oral microbiome genomic and proteomic leached from the original skeletal source, as well as environmental and human proteins. Despite this, both the original element and concretions lacked endogenous human aDNA, indicating that the use of this type of material in future molecular archaeological applications is limited.