PXD056371

PXD056371 is an original dataset announced via ProteomeXchange.

Title	Proteomics of human adipose and umbilical cord mesenchymal stem cell-derived extracellular vesicles
Description	MSC-EV exerts their effects by transferring cargo components into target cells. Given that extracellular vesicles (EV) can deliver diverse cargo to recipient cells and elicit similar therapeutic effects, we investigate the cargo of both adipose-derived MSC-derived EV (AMSC-EV) and umbilical cord-derived MSC-derived EV (HUMSC-EV).As a crucial component of EV cargo, proteins are known to exert significant influence on EV functions. We performed a protein analysis of MSC-EV.
HostingRepository	PRIDE
AnnounceDate	2025-05-07
AnnouncementXML	Submission_2025-05-07_03:21:04.663.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Huan Zhang
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2024-09-30 01:59:11	ID requested
⏵ 1	2025-05-07 03:21:06	announced

10.1038/s41392-024-01993-z;

Zhang H, Xiao X, Wang L, Shi X, Fu N, Wang S, Zhao RC, Human adipose and umbilical cord mesenchymal stem cell-derived extracellular vesicles mitigate photoaging via TIMP1/Notch1. Signal Transduct Target Ther, 9(1):294(2024) [pubmed]

submitter keyword: mesenchymal stem cell, extracellular vesicles,human

Robert Chunhua Zhao
contact affiliation	Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, China.
contact email	zhaochunhua@ibms.pumc.edu.cn
lab head
Huan Zhang
contact affiliation	Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, China.
contact email	zhanghuan@ibms.pumc.edu.cn
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD056371

PRIDE project URI

• PRIDE
  1. PXD056371
     1. Label: PRIDE project
     2. Name: Proteomics of human adipose and umbilical cord mesenchymal stem cell-derived extracellular vesicles