A proteomic analysis using co-immunoprecipitations (Co-IPs) coupled to mass spectrometry to compare the FLS2 interactomes induced by the natural ligand or the surrogates. proFLS2:FLS2-GFP line was used for treatment either DMSO, Maya1, Maya2, or flg22 and wild-type (Col 0) was used for negative control treatment with flg22.