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PXD051935

PXD051935 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleIP-MS analysis of Legionella pneumophila SdcB for detecting noncanonical ubiquitin crosslink by Legionella transglutaminase MavC.
DescriptionTo identify the unique ubiquitin conjugation to Legionella pneumophila SdcB, we investigated the modified SdcB by IP-MS analysis. We revealed that a Legionella transglutaminase MavC has a catalytic activity to crosslink Gln residues of ubiquitin to Lys residues of SdcB, resulting in a noncanonical ubiquitin modification, and that this modification abolish the enzymatic activity of SdcB as a E3 ubiquitin ligase.
HostingRepositoryjPOST
AnnounceDate2024-05-02
AnnouncementXMLSubmission_2024-05-02_01:31:18.786.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterCore Instrumentation Facility
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListS-carboxamidomethyl-L-cysteine; L-methionine sulfoxide; Acetyl; deamidated L-glutamine; deamidated L-asparagine
Instrumentinstrument
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-05-01 21:49:13ID requested
12024-05-02 01:31:19announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Legionella pneumophila, SdcB, MavC, ubiquitin, transglutaminase
Contact List
Tomoko Kubori
lab head
Core Instrumentation Facility
contact affiliationThe University of Osaka
dataset submitter
Full Dataset Link List
jPOST dataset URI
Dataset FTP location
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