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PXD050191

PXD050191 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleAnalysis of ZNF827 Halotag pulldown for a manuscript titled ‘ZNF827 is a single-stranded DNA binding protein that regulates the ATR-CHK1 DNA damage response pathway’
DescriptionMass spectrometry analysis of ZNF827 Halotag pulldown ZNF827 pull-downs were performed in HEK 293T cells overexpressing HaloTag ZNF827 or empty vector control using the HaloTag® Protein Pull-Down and Labelling System (Promega) according to the manufacturer’s protocol. Pull-downs were subjected mass spectrometry (MS) for purity validation.
HostingRepositoryPRIDE
AnnounceDate2024-06-23
AnnouncementXMLSubmission_2024-06-23_01:16:38.456.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterChristopher Nelson
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListmonohydroxylated residue; deaminated residue; iodoacetamide derivatized residue
InstrumentTripleTOF 6600
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-02-27 07:36:51ID requested
12024-06-23 01:16:39announced
Publication List
10.1038/s41467-024-46578-0;
Yang SF, Nelson CB, Wells JK, Fernando M, Lu R, Allen JAM, Malloy L, Lamm N, Murphy VJ, Mackay JP, Deans AJ, Cesare AJ, Sobinoff AP, Pickett HA, ZNF827 is a single-stranded DNA binding protein that regulates the ATR-CHK1 DNA damage response pathway. Nat Commun, 15(1):2210(2024) [pubmed]
Keyword List
submitter keyword: ATR, ssDNA,ZNF827, DNA damage response
Contact List
Hilda Pickett
contact affiliationChildren's Medical Research Institute. Telomere Length Regulation Unit.
contact emailhpickett@cmri.org.au
lab head
Christopher Nelson
contact affiliationChildren's Medical Research Institute
contact emailcnelson@cmri.org.au
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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