In this study, M. alba cell suspension culture established after young stems were treated with elicitors methyl-beta-cyclodextrin combined with methyl jasmonate at 50mM and 0.1mM concentration, respectively. Elicited and control cell cultures were sampled at 0, 6, 12, 24, 48 and 72 hours and used for stilbene analysis in both the extracellular and intracellular medium, and for RNA and protein extraction. RNAseq and label-free proteomic analysis was then performed. All time point series were used for transcriptomic and 24, 48 and 72 hours time points the proteomic analysis. Transcriptomic data were used to reannotate the genome draft published by (Jiao et al. (2020), Molecular Plant, 13(7), 1001-1012) and to update the M. alba transcript and peptide database. MS-based protein identification greatly benefit from the reannotated database. A multiomics analysis was performed to search for candidates of stilbene biosynthesis in M. alba.