PXD047543

PXD047543 is an original dataset announced via ProteomeXchange.

Title	Next generation mapping of the salicylic acid signaling hub and transcriptional cascade
Description	For over 60 years, salicylic acid (SA) has been known as a plant immune signal required for both basal and systemic acquired resistance (SAR). SA activates these immune responses by reprogramming up to 20% of the transcriptome through the function of NPR1. However, components in the NPR1-signaling hub, which appears as nuclear condensates, and the cascade of the NPR1-signaling pathway remained elusive due to difficulties in studying transcriptional cofactors whose chromosomal associations are often indirect and transient. To overcome this challenge, we applied TurboID to divulge the NPR1-proxiome, which detected key known NPR1-interactors and many new components of transcription-related complexes.
HostingRepository	PRIDE
AnnounceDate	2025-05-06
AnnouncementXML	Submission_2025-05-06_12:19:37.892.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Shouling Xu
SpeciesList	scientific name: Arabidopsis thaliana (Mouse-ear cress); NCBI TaxID: 3702;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2023-12-05 12:04:04	ID requested
⏵ 1	2025-05-06 12:19:38	announced

10.1016/j.molp.2024.08.008;

Powers J, Zhang X, Reyes AV, Zavaliev R, Ochakovski R, Xu SL, Dong X, Next-generation mapping of the salicylic acid signaling hub and transcriptional cascade. Mol Plant, 17(10):1558-1572(2024) [pubmed]

submitter keyword: NPR1-proxiome, Proximity labeling, TurboID, LC-MS/MS

SHOULING XU
contact affiliation	Carnegie Mass Spectrometry Facility
contact email	SXU@ciw.edu
lab head
Shouling Xu
contact affiliation	Carnegie Institution at Stanford
contact email	sxu@ciw.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD047543

PRIDE project URI

• PRIDE
  1. PXD047543
     1. Label: PRIDE project
     2. Name: Next generation mapping of the salicylic acid signaling hub and transcriptional cascade