PXD047094

PXD047094 is an original dataset announced via ProteomeXchange.

Title	Mutant p53 interactome study with IP-MS
Description	Inactivating TP53 mutations lead to a loss of function of p53, but can also often result in oncogenic gain-of-function (GOF) of mutant p53 (mutp53) proteins which promote tumor development and progression. The GOF activities of TP53 mutations are well documented, but the mechanisms involved remain poorly understood. Here, we study the mutp53 interactome with IP-MS.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_06:15:58.741.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Zhen Chen
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2023-11-20 03:54:40	ID requested
1	2023-11-27 10:36:12	announced
⏵ 2	2024-10-22 06:15:59	announced	2024-10-22: Updated project metadata.

Dataset with its publication pending

submitter keyword: MS, IP, mutant p53,p53

Junjie Chen
contact affiliation	Experimental Radiation Oncology department, The University of Texas MD Anderson Cancer Center
contact email	jchen8@mdanderson.org
lab head
Zhen Chen
contact affiliation	MD Anderson Cancer Center
contact email	zhenchen2014@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/11/PXD047094

PRIDE project URI

• PRIDE
  1. PXD047094
     1. Label: PRIDE project
     2. Name: Mutant p53 interactome study with IP-MS