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PXD046752 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleDirect-to-biology: Accelerated E3 ligase modulator discovery
DescriptionQuatintative analysis of the effects of the E14 compound on the proteome of MM.1S cells.
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterValeriia Sapozhnikova
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-11-07 11:06:38ID requested
12024-01-26 07:24:47announced
Publication List
Wang Z, Shaabani S, Gao X, Ng YLD, Sapozhnikova V, Mertins P, Kr, ö, nke J, D, ö, mling A, Direct-to-biology, automated, nano-scale synthesis, and phenotypic screening-enabled E3 ligase modulator discovery. Nat Commun, 14(1):8437(2023) [pubmed]
Keyword List
submitter keyword: MM.1S, degraders, multiple myeloma
Contact List
Philipp Mertins
contact affiliationMax-Delbrück-Centrum für Molekulare Medizin (MDC)
contact emailPhilipp.Mertins@mdc-berlin.de
lab head
Valeriia Sapozhnikova
contact affiliationMax Delbrück Center
contact emailvaleriia.sapozhnikova@mdc-berlin.de
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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