PXD046130

PXD046130 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Intact mass LC-MS analysis of Flu B HA1 and HA2 proteins
Description	To determine the sequences of the Flu HA1 and HA2 proteins, we performed intact mass LC-MS analysis. By reducing disulfide bridges two peaks corresponding to the HA1 and HA2 components were detected. Mass profiles were obtained for both glycosylated and deglycosylated HA proteins.
HostingRepository	PRIDE
AnnounceDate	2025-05-06
AnnouncementXML	Submission_2025-05-06_11:49:51.326.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sem Tamara
SpeciesList	scientific name: Influenza A virus (A/Aquatic bird/Hong Kong/M603/98(H11N1)); NCBI TaxID: 129775;
ModificationList	complex glycosylation
Instrument	Xevo G2-S QTof

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-10-13 10:22:22	ID requested
⏵ 1	2025-05-06 11:49:52	announced

Publication List

Juraszek J, Milder FJ, Yu X, Blokland S, van Overveld D, Abeywickrema P, Tamara S, Sharma S, Rutten L, Bakkers MJG, Langedijk JPM, Engineering a cleaved, prefusion-stabilized influenza B virus hemagglutinin by identification and locking of all six pH switches. PNAS Nexus, 3(10):pgae462(2024) [pubmed]
10.1093/pnasnexus/pgae462;

Juraszek J, Milder FJ, Yu X, Blokland S, van Overveld D, Abeywickrema P, Tamara S, Sharma S, Rutten L, Bakkers MJG, Langedijk JPM, Engineering a cleaved, prefusion-stabilized influenza B virus hemagglutinin by identification and locking of all six pH switches. PNAS Nexus, 3(10):pgae462(2024) [pubmed]

10.1093/pnasnexus/pgae462;

Keyword List

submitter keyword: intact mass, HA2, HA1,Flu B

submitter keyword: intact mass, HA2, HA1,Flu B

Contact List

Johannes P.M. Langedijk
contact affiliation	Viral Vaccines, Janssen Vaccines, Leiden, The Netherlands
contact email	HLangedi@its.jnj.com
lab head
Sem Tamara
contact affiliation	Janssen
contact email	semyon.tamara@gmail.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD046130
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD046130

PRIDE project URI

Repository Record List

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