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PXD044643

PXD044643 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleTargeted RNase H-mediated Extraction of crosslinked RBPs (TREX) for assessing U1 RNA interactome
DescriptionWe used Targeted RNase H-mediated Extraction of crosslinked RBPs (TREX)to assess the endogenous binding partners of U1 small nuclear RNA (U1 snRNA) in human HCT116 cells. Extracted proteins from U1 digested and control cells (5 replicate per condition) were compared, using label-free (LFQ) Quantitative proteomics.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_06:18:39.438.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterFaraz Mardakheh
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListphosphorylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive Plus
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-08-18 08:36:08ID requested
12023-12-27 08:18:39announced
22024-10-22 06:18:39announced2024-10-22: Updated project metadata.
Publication List
10.1101/2023.06.30.547259;
Keyword List
submitter keyword: TREX
RBP
RNA Interactome
LC-MS/MS
Quantitative proteomics
Contact List
Faraz Mardakheh
contact affiliationCentre for Cancer Cell & Molecular Biology Barts Cancer Institute Queen Mary University of London Charterhouse Square London EC1M 6BQ U.K.
contact emailf.mardakheh@qmul.ac.uk
lab head
Faraz Mardakheh
contact affiliationBarts Cancer Institute
contact emailf.mardakheh@qmul.ac.uk
dataset submitter
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Dataset FTP location
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